Class I: Sodium channel blocker
--Ia: lengthen the action potential: quinidine, procainamide, disopyramide
--Ib: shorten action potential: lidocaine, mexitil
--Ic: no effect: propafenone

 

Class II: Beta-blocking agents
--carvedilol, propranolol, esmolol, timolol, metoprolol, atenolol, bisoprolol

 

Class III: Potassium channel blocker (Prolong action potential without affecting sodium)
--amiodarone, sotalol, ibutilide, dofetilide, dronedarone

 

Class IV: Calcium channel blocker
--verapamil, diltiazem

 

Class V: Unknown mechanism or Direct nodal inhibitation
--adenosine, digoxin, magnesium Sulfate


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